Consistently, OSS markedly inhibited MerTK expression and induced endothelial dysfunction shown as decreased expression of endothelial nitric oxide synthase (eNOS), Gas 6 (ligand of MerTK), and transforming growth factor-β (TGF-β, anti-inflammatory cytokine) (Figure 1M). The gene discussed is TGFB1; the disease is endothelial dysfunction.