KLK3 and prostate adenocarcinoma: A 74-year old patient (Figure 4) was newly diagnosed with locally advanced prostate adenocarcinoma Gleason 9 cT3b cN1 cM0 (International Society of Urological Pathology (ISUP) grade group 4), with positive biopsy probes in 8/8 samples and an initial prostate-specific antigen (iPSA) level of 4.69 ng/mL.