Additionally, IL4R-Abx increased the M1-macrophage population (Figure 8H) and CD8+ T-cell/Treg ratio (Figure 8J), while decreasing the M2-macrophage (Figure 8I) and MDSC population (Figure 8K) in LLC tumor tissues at higher levels than Abx and Ctrl-Abx. The gene discussed is CD8A; the disease is neoplasm.