CD8A and neoplasm: Compared to Abx and Ctrl-Abx, IL4R-Abx more efficiently increased the population of M1-macrophage (Figure 7E and S9B) and CD8+ T-cells (Figure S9B and S9C) and CD8+ T-cell/Treg ratio (Figure 7G), while reducing the population of M2 macrophages (Figure 7F and S9B), MDSCs (Figure 7H and S9B), and Tregs (Figure S9B and S9D) in the tumor microenvironment.