Upregulation of ITGAL expression was strongly associated with immunomodulators, chemokines, and levels of CD8+ T cells, CD4+ T cells, B cells, monocytes, neutrophils, macrophages, T cells, natural killer (NK) cells, and myeloid dendritic cell infiltration in gastric adenocarcinomas (STAD). The gene discussed is CD8A; the disease is gastric adenocarcinoma.