CD4 and gastric adenocarcinoma: Some studies have reported that the upregulation of ITGAL expression was closely associated with the level of infiltration of immunomodulators, chemokines, CD8+, CD4+ T cells, B cells, monocytes, neutrophils, macrophages, T cell modulators, NK cells, and myeloid dendritic cells in gastric adenocarcinoma (STAD) (19).