Nonetheless, the L-fuc-increased in vivo anti-tumor immunity (Figure 1A) and the T cell activation levels (Figures 2, 4E, F) are certainly attributed to additional L-fuc-regulated factors beyond MHC complex expression/presence that are associated with cross-presentation, such as antigen uptake and processing, which we have shown to be increased by L-fuc (Figures 2A–E). Here, HLA-C is linked to neoplasm.