Patients with SLE had disturbance of the immune system by a decreased number of various lymphocyte subsets. Especially those suffering from infections. Preliminary findings suggest that the low absolute number of these cells may be an indicator of possible infection in SLE patients and low-dose IL2 therapy proves to enhance the ability to resist infection in SLE patients by restoring a decreased number of lymphocyte subpopulations. Here, IL2 is linked to systemic lupus erythematosus.