To further elucidate the mechanism by which MSI2 and RBM17 induce radioresistance in lung cancer cells, we performed immunofluorescence detection of MSI2 and RBM17 in A549 cells at 0, 0.5, 4, 8, 12, and 24 h post‐irradiation with 8 Gy. The gene discussed is RBM17; the disease is lung cancer.