Based on the above results, we have drawn a schematic diagram of MSI2, RBM17, and ATR in lung cancer radiotherapy (Figure 7), which shows that lung cancer cells undergo DNA damage repair after radiation exposure and emit certain signals, RBM17 may first sense the signal and enter the nucleus, while recruiting MSI2 and assisting MSI2 to enter the nucleus. The gene discussed is ATR; the disease is lung cancer.