The inhibition of the TGF-β1/Smad classic signaling pathway and the reversal of epithelial-mesenchymal transition are among the mechanisms through which Cordyceps sinensis exerts its anti-renal fibrosis effects (Wang et al., 2018; Yang et al., 2020; Zhang et al., 2022). This evidence concerns the gene TGFB1 and renal fibrosis.