TNF and ulcerative colitis: Oral administration of CTZ (20 mg/kg) and LOR (10 mg/kg) for 7 days after induction of ulcerative colitis, showed a significant P>0.05 decrease in TNF-α (60.39±1.97 and 53.02±0.76 pg/mg protein, respectively) as compared to AA group (3.21 and 3.66 fold decrease, respectively).