Notable examples of digital tools relevant to T2DM patients include websites (e.g., diabetes associations websites) and social media (e.g., Facebook forums), providing information, and mobile apps such as nutrition apps (18), physical activity apps (19), glucose monitoring apps (20), insulin titration apps (18), digital home glucose meters (glucometers) (21), bluetooth-enabled blood glucose meters (22) and T2DM treatment AI-based algorithms (23). The gene discussed is INS; the disease is type 2 diabetes mellitus.