Based on the analysis of PD1/PDL1 signaling pathways in the Damien treatment proliferation stage of DR study confirmed that the mechanism of Damien drinks Chinese traditional medicine preparation can improve the proliferation period diabetes complications in patients with retinal visual acuity level, and the process may be through inhibiting patient PD1/PDL1 signal transduction protein expression and activation to restore the function of mononuclear cells, The monocytes are transformed to inhibit inflammation and inhibit the expression of related inflammatory factors [18,19]. The gene discussed is CD274; the disease is diabetes mellitus.