Therefore is of no surprise, that recent studies evidenced increased inflammatory markers in patients with pituitary adenomas, in specific patients with Cushing disease, and with much less extent in acromegaly and PRL patients compared to non-functioning adenoma (28, 29) To our knowledge, only one study focused on this topic in patients with PRL, who found some differences in the hemostatic parameters in comparison to healthy controls (42). Here, PRL is linked to acromegaly.