The clinical significance of LINK-A in tumors has drawn considerable attention (Lin et al., 2016; Lin et al., 2017; Filippov-Levy et al., 2018; Ma and Xue, 2018; Zhao et al., 2018; Zhang et al., 2019a; Zhang et al., 2019b; Chen et al., 2019; Hua et al., 2019; Liu et al., 2019; Zhao et al., 2019; Kong et al., 2020; Li et al., 2020; Maleki et al., 2020; Zhang et al., 2020; Ghahfarokhi et al., 2023; Nan et al., 2023), evident in its dysregulated expression profiles observed in both tumor tissues and blood samples across various malignant tumors (Table 2). This evidence concerns the gene LINC01139 and cancer.