The most important limiting factor of our study is therelatively low number of patients, considering the prevalence of BC.Although our results are consistent with the literature, studies withlarger sample sizes and meta-analyses are needed for generalization.The relationship between BRCA2 and ipsilateral breastcancer, which is one of the intriguing findings in our study, shouldbe further investigated in future research. The gene discussed is BRCA2; the disease is breast cancer.