Examples of such shared TFs between NEPC and SCLC subtypes included: ASCL1, HOXB5, ETS2, ELF3, XBP1 and PROX1 (ASCL1 subtype), and NEUROD1, HES6, TCF4, NFIA, and JARID2 (NEUROD1 subtype). The gene discussed is HOXB5; the disease is small cell lung carcinoma.