Even though the HERV-W-env expression was not significantly higher in BD patients (p = 0.054), significant positive correlations between HERV-W-env expression and TNF-α/IL-10 and IFN-γ/IL-10 ratios, as well as significant negative correlation observed between the level of HERV-W-env expression and circulating IL-10, were found. The gene discussed is TNF; the disease is Behcet disease.