Notably, those with sarcopenia had significantly lower ABI (1.04 ± 0.16 vs. 1.08 ± 0.15, P = 0.028 for the right ABI; 1.01 ± 0.16 vs. 1.06 ± 0.16, P = 0.002 for the left ABI) and VRI (0.83 ± 0.57 vs. 1.08 ± 0.56, P < 0.001) and higher serum levels of ICAM‐1 (P < 0.001), VCAM‐1 (P = 0.003) and ET‐1 (P = 0.037). This evidence concerns the gene EDN1 and sarcopenia.