TFRC and hydrops fetalis: High serum transferrin receptors identify patients at high risk of death beyond standard prognostic variables.54, 55, 56, 57 In addition, his analysis found that TSAT <20% and serum iron ≤13 μmol/L were associated with a higher mortality, and this was independent of HF phenotype, and this is when iron supplementation should be warranted to reduce the chance of mortality.45