CD274 and neoplasm: Similarly, we noted a similar pattern of decreased PD-L1+ tumor cells in LvM compared to BrT across all subtypes: HER-2+ (14.8% vs. 43.9%, q-value = 0.0110, HR+/HER-2− (11.0% vs. 22.1%, q-value < 0.0001), TNBC (18.3% vs. 48.5%, q-value < 0.0001) (Supplemental Fig. 2, Supplemental Table 2b).