When the three markers were compared to other malignancies, including ampulla of Vater carcinoma (AoVCa), biliary carcinoma (BCA), neuroendocrine tumour of the pancreas (NET), pancreatic cyst or pseudocysts (PC), lung cancer (LC), colon cancer (CoCa) and IPMN, only IL-10R2+ cells were significantly elevated in PDAC (Fig. 1d). This evidence concerns the gene IL10RB and pachyonychia congenita.