The key cancer-related genes affected by HPV integrants are Diaphanous-related formin 2 (DIAPH2) gene rearrangements and Tumour protein 63 (TP63) gene promoter aberration and Proviral integration site for Moloney murine leukaemia virus 1 (PIM1) and Forkhead box E1 (FOXE1) gene amplification [63]. Here, DIAPH2 is linked to cancer.