CASP8 and kidney disorder: We also found, using the Olink proteomic platform, that TNF-α and TMAO enhanced the secretion of additional inflammatory-and growth mediators associated with kidney disease; VEGFA, GDNF, CDCP1, OPG, uPA, AXIN1, MMP-1, MMP-10, PD-L1, HGF, Flt3L, 4E-BP1, CD40, CASP-8, ADA, TNFRSF9, TWEAK44–61.