CD44 and diabetic kidney disease: This study still has certain limitations that we aim to address progressively in the future.Firstly, Despite our pioneering discovery and validation of the functions of ferroptosis regulators CD44 and ZFP36 in DKD and immune infiltration, it remains imperative to ascertain the potential biological roles of ZFP36 and CD44.Another limitation is the absence of verification for the interactions between CD44, ZFP36, ferroptosis, and macrophages in DKD through other functional or in vitro studies.