Table S2 lists that LGALS3 demonstrated a significant positive association with various immune cell biomarkers, including B cell (CD19 and CD79A), CD4+ T cell (CD4), CD8+ T cell (CD8A and CD8B), neutrophil (ITGAM and CCR7), M1 macrophage (NOS2, IRF5, and PTGS2), M2 macrophage (CD163, VSIG4, and MS4A4A), dendritic cell (HLA-DPB1, HLA-DQB1, HLA-DRA, HLA-DPA1, CD1C, NRP1, and ITGAX) and CAFs (FAP, ACTA2, S100A4, PDPN, PDGFR, and CD70) in HCC. This evidence concerns the gene IRF5 and hepatocellular carcinoma.