Other markers, such as PS100, MelanA, HMB45, SOX10, Chromogranin, Synaptophysin, CD56, PAX8 and a large panel of cytokeratins (CK7, CK20, panCK, MNF116), were all negative (not shown), eliminating melanoma, PEComa and carcinoma (notably renal cell carcinoma). This evidence concerns the gene PAX8 and hereditary clear cell renal cell carcinoma.