Other markers, such as PS100, MelanA, HMB45, SOX10, Chromogranin, Synaptophysin, CD56, PAX8 and a large panel of cytokeratins (CK7, CK20, panCK, MNF116), were all negative (not shown), eliminating melanoma, PEComa and carcinoma (notably renal cell carcinoma). Here, PMEL is linked to neoplasm with perivascular epithelioid cell differentiation.