CD8A and neoplasm: For mice cured by the cervical cancer vaccines, the proportions of CD8+ T cells (P < 0.001) and NK cells (P < 0.05) in the spleen were significantly higher than those of tumor-bearing mice in the PBS or the LM∆ and LI∆ group, and the proportion of M1-type macrophages and M1/M2 ratio were also relatively high (P > 0.05) (Fig. 3A–E).