Mediterranean diet not only plays an obvious role in blood glucose control, weight reduction, and risk reduction of heart disease, etc. Furthermore, studies have shown that Mediterranean diet affects glucagon‐like peptide 1 [42], oxyntomodulin [43], postprandial lipemia [44], and antioxidant/ antioxidant enzymes compounds [45], gut microbiota composition and function [46, 47], branched chain aminoacid management [48] and many other aspects have certain significance. This evidence concerns the gene GCG and heart disorder.