Pairwise correlations for these four genes across 173 AML patients from TCGA were analyzed, and the data are summarized in Supplemental Fig. S1G. The results showed positive correlations between CDK6 and MLL, and between CDK6 and FLT3 expression (to a lesser degree, also between FLT3 and MLL), which is consistent with the previous reports8–10,12–14. Here, KMT2A is linked to acute myeloid leukemia.