CDK6 and cancer: To this end, we first examined the publicly available AML data (gepia.cancer-pku.cn) and found that the CSF1R gene is overexpressed in many AML patient samples (Supplement Fig. S1A), similar to several other AML-implicated targets previously, FLT3 (Supplement Fig. S1B), MLL (Supplement Fig. S1C) and CDK6 (Supplement Fig. S1D).