qRT-PCR analysis of clinical samples revealed that compared with those in the healthy control group, the expression levels of CYP8B1 and CYP7A1 were significantly upregulated in the ITP group (Fig. 6a,b),however, the ADH4, CYP1A2, and NR1H4 genes were not differentially expressed (Fig. 6c–e). This evidence concerns the gene CYP7A1 and autoimmune thrombocytopenic purpura.