Moreover, GSEA results showed that B cell receptor signaling pathway, chronic myeloid leukemia, FC-gamma-R- mediated phagocytosis, pathogenic Escherichia collineation and spliceosome were mainly enriched in AP samples or low expression Prdx4 group (Fig. 3C). Here, PRDX4 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.