Individuals with a germline mutation in BRCA1 exhibit a chance of 48.3% for ovarian cancer by 70 years old (95% confidence interval [CI] = 38.8–57.9%) and of 20% (95% CI = 13.3–29.0%) when the mutation is in BRCA2 [5]. The gene discussed is BRCA1; the disease is ovarian carcinoma.