For the OB dataset, ITree instantly generated a tree with perfect classification for the rule: if PPARGC1B is smaller than the obesity-related lncRNA SLC25A21_AS1, then classify as “not obese,” otherwise “obese.” For the HCC dataset, the ITree system also found a tree with a single TSP rule in under a minute that could classify 98% of the data correctly. This evidence concerns the gene PPARGC1B and obesity due to melanocortin 4 receptor deficiency.