The Src-like kinase p61HcK is required for the construction of comets, like F-actin structures in lysosomes and at the tip of tyrosine-phosphorylated CagA, and it has been reported to inhibit SKF activation, which triggers proinflammatory and antiapoptotic responses in the gastric epithelium that are chronically detrimental to the human host.[62] Additionally, the role of HCK in the development of atherosclerosis cannot be ignored. This evidence concerns the gene FYN and atherosclerosis.