We found that males (β = −0.147, 95% CI: −0.234 to −0.060, P < .01), hypertension (β = −0.970, 95% CI: −1.055 to −0.885, P < .01), diabetes (β = −0.357, 95% CI: −0.474 to −0.239, P < .01), PaCO2 (β = −0.003, 95% CI: −0.006 to −0.000, P < .01) and the length of the hospital stay (β = −0.017, 95% CI: −0.029 to −0.006, P < .01) were negatively correlated to the ln-T-IgE. The gene discussed is IGHE; the disease is diabetes mellitus.