Newly published data emerged after the Fever RCT commenced that shows a link between cerebral malaria, acute kidney injury and the development chronic kidney disease (CKD), [36] so the development of CKD after CNS malaria will also be compared using creatinine and the urine albumin:creatinine ratio (ACR) assessed at least 6-months post-recovery. The gene discussed is ALB; the disease is chronic kidney disease.