Eleven genes were found to be more essential in cancer cell lines with high expression of MEMO1 (GOF-GIs, Supplementary file 1A), six genes were more essential in the cell lines with low-MEMO1 levels (LOF-GIs, Supplementary file 1B), and one (FTH1) showed inconsistent types of interactions between different databases. The gene discussed is FTH1; the disease is cancer.