HLA-C and asthma: We further filtered them based on the involvement in pathway ‘TNFR2-NFKB pathway’ and ‘innate lymphocyte [ILC] development’, since these pathways were most significantly associated with asthma (Figure 3), even after excluding MHC region (p = 2.57 × 10−13 and 1.39 × 10−17).