Next, we investigated whether T227 phosphorylation influenced HCC metastasis in Huh7 and PLC/PRF/5 cells transfected with exogenous wild‐type G3BP2 (Flag‐G3BP2‐WT) or T227 mutant G3BP2 (Flag‐G3BP2‐Mu). The gene discussed is G3BP2; the disease is hepatocellular carcinoma.