We found that in the presence of β‐catenin inhibitor ICG001 and HIF‐1α inhibitor PX‐478, the upregulation of glycolysis‐related genes PKM2, GLUTA, HK2, and LDHA in gastric cancer cells by M2‐EX was greatly attenuated (Figure 6A,B). This evidence concerns the gene HK2 and gastric cancer.