Persistent RSV detection in stable COPD patients has been shown to cause airway inflammation as measured by sputum interleukin (IL)-6, IL-8, and myeloperoxidase levels and a rapid decline in lung functions, particularly forced expiratory volume in one second (FEV1) (Seemungal et al., 2001). Here, CXCL8 is linked to chronic obstructive pulmonary disease.