To determine the role of RUNX1 in deregulating genes in FLT3i relapse we overlapped our 2-fold deregulated set of genes after FLT3i relapse with a RUNX1 chromatin-immunoprecipitation (ChIP-Seq) dataset from 2 primary FLT3-ITD+ AML samples and MOLM1414. This evidence concerns the gene RUNX1 and acute myeloid leukemia.