INS and obesity due to melanocortin 4 receptor deficiency: The result was contrary to our initial hypothesis but suggests other factors that are associated with higher baseline HbA1c concentration, such as insulin delivery (basal or bolus dosing), carbohydrate-to-insulin ratios, or overweight/obesity may be of greater impact on daily glycemic TIR than overall diet quality among persons with an elevated HbA1c to start.