To date, only one drug is FDA-approved for acute ischemic stroke treatment: tissue plasminogen activator (tPA), also known as alteplase (The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group, 1995; Kleindorfer et al., 2008; Lees et al., 2010; Powers et al., 2015). The gene discussed is PLAT; the disease is stroke disorder.