Chronic kidney disease (CKD) is a condition affecting a substantial proportion of the general population; the overall prevalence of CKD stages III–V according to the Kidney Disease Improving Global Outcomes (KDIGO) guidelines ranges from 2% to 17%, with estimates of higher prevalence when including patients in earlier stages (abnormal urinary albumin excretion with preserved estimated glomerular filtration rate [eGFR]) (1). The gene discussed is ALB; the disease is chronic kidney disease.