STING1 and cancer: Activated STING triggers the phosphorylation and activation of TBK1 and IRF3.[63] Phosphorylated IRF3 (p‐IRF3) forms dimers and translocates into the nucleus, where it induces the expression of IFNs and other inflammatory cytokines.[61] Based on this signaling cascade, we conducted Western blotting on BM‐MSCs from the DC with cancer cells and observed increased levels of phosphorylated (p)‐STING, p‐TBK1, and p‐IRF3 in BM‐MSCs following the DC compared to those without DC (Figure 6B).