While in the previous study, a peptide with cell penetration enhancing properties was used as a nanocarrier for the anti-inflammatory agent, Chen et al. employed an antimicrobial peptide nanogel as a nanocarrier for the anti-inflammatory agent, TNF-Related Apoptosis-Inducing Ligand (TRAIL), for effective sepsis management [206]. The gene discussed is TNFSF10; the disease is Sepsis.