One case with three fusions (EP300::BCOR; BCOR::L3MBTL2; BCOR::EP300) was described as a neuroepithelial tumor with small spindle cell pattern and spongioblastoma polar-like or ependymoma-like areas, calcifications, chicken-wire vasculature, necrosis, high mitotic activity and seemed to fit the archetypical histological pattern of CNS tumors with BCOR/BCOR(L1)-fusion. Here, BCOR is linked to central nervous system neoplasm.