TTN and neoplasm: The results showed that compared to the NC group, overexpression of TTN-AS1 and CTC-derived exosomes co-cultured with Huh28 cells significantly increased the average tumor volume and average tumor weight, while TTN-AS1-depleted exosomes co-cultured with Huh28 cells significantly reduced the average tumor volume and average tumor weight (Fig. 7A-C).