Importantly, NDUFC1 has the highest gene expression ratio in the N + compared to the N0 status of lung SCC, and interestingly, in line with our findings, it is associated with a higher risk of lymphatic metastasis, a higher proportion of positive lymph nodes, and a more advanced tumor stage in gastric cancer [35] and hepatocellular carcinoma [36]. Here, NDUFC1 is linked to neoplasm.