UQCRC2 and neoplasm: Other proteins of our founded subnetwork, including COX4I1, UQCRC2, ATP5J (ATP5PF), and ENSP00000400168 (ATP5MF-PTCD1), and UQCRQ also play a role in mitochondrial ATP synthesis; they are also involved in tumor initiation, growth, and metastasis [37].