He et al. found that ZFPM2-AS1 acts as a miRNA sponge and promotes cell invasion by regulating miR-139/GDF10 in HCC [27], Ma et al. Found that DANCR was up-regulated in tumor tissues and plasma of patients with HCC, and its expression was highly correlated with microvascular and liver capsule invasion of HCC [28], MKLN1-AS [29], LNCSRLR [30] and AL137186.2 [31] also are associated with the prognosis of patients with HCC, which are consistent with our findings. The gene discussed is MKLN1; the disease is neoplasm.